Viper Medical Scientist Profile: Wei Xunbin
2025-11-03
Wei Xun bin, Tenured Full Professor (Boya Professor) at Peking University
- Received a Bachelor's degree in Optoelectronic Technology from the Department of Physics, University of Science and Technology of China (USTC) in 1993.
- Earned a PhD in Biophysics from the University of California, Irvine (UC Irvine) in 1999.
- Conducted postdoctoral research at Harvard Medical School from 1999 to 2001.
- Served as a Research Assistant Professor at Harvard Medical School from 2001 to 2006.
- Returned to China in 2006 and held positions as a Researcher, Vice Dean of the Institute of Biomedical Engineering at Fudan University, and Professor in the Department of Chemistry.
- Has published over 80 SCI-indexed papers in journals including Nature and PNAS, with more than 4,000 citations.
- Obtained one registration certificate for Class III medical devices in China and five patents (domestic and international).
- Previously served as a Distinguished Professor at Shanghai Jiao Tong University (affiliated with the School of Biomedical Engineering and MED-X Institute). Currently, he is a Tenured Full Professor (Boya Professor) at Peking University, Head of the Biomedical Device Discipline, and recipient of the National Outstanding Youth Fund.
- Holds academic honors and positions including Fellow of the International Society for Optics and Photonics (SPIE), Vice President of the Medical Device Committee of the Chinese Society for Instrumentation, Vice Chairman of the Laser Medicine Committee of the Chinese Optical Society, Standing Committee Member of the Molecular Imaging Professional Committee of the Chinese Biophysical Society, and Standing Committee Member of the Biomedical Photonics Professional Committee of the Chinese Optical Society.
- Currently serves as Associate Editor of the journal Cytometry Part A (impact factor: 3.71) – a leading publication in the field of cell analysis – and as an expert reviewer for the Medical Science Division of the National Natural Science Foundation of China (NSFC).
- His main research focuses on optical 3D imaging and detection technologies for tumors and immunity, as well as phototherapy technologies for Alzheimer's disease.
Representative Papers
- Wang L, Fan Z, Zhang J, Changyi Y, Huang C, Gu Y, Xu Z, Tang Z, Lu W, Wei X, Li C.Evaluating tumor metastatic potential by imaging intratumoral acidosis via pH-activatable near-infrared fluorescent probe. Int J Cancer. 2014 Epub. (corresponding author; impact factor: 6.2)
- Zhang Y, Cai W, Huang Q, Gu Y, Shi Y, Huang J, Zhao F, Liu Q, Wei X, Jin M, Wu C, Xie Q, Zhang Y, Wan B, Zhang Y. Mesenchymal stem cells alleviate bacteria-induced liver injury in mice by inducing regulatory dendritic cells. Hepatology. 2014, 59(2):671-82. (impact factor: 11.19)
- Zhong MC, Wei XB, Zhou JH, Wang ZQ, Li YM. Trapping red blood cells in living animals using optical tweezers. Nat Commun. 2013,4:1768. (corresponding author; impact factor: 10.7)
- Liao Y, Cheng Y, Liu C, Song J, He F, Shen Y, Chen D, Xu Z, Fan Z, Wei X, Sugioka K, Midorikawa K. Direct laser writing of sub-50 nm nanofluidic channels buried in glass for three-dimensional micro-nanofluidic integration. Lab Chip. 2013, 13(8):1626-31. (impact factor: 5.8)
- Fan ZC, Yan J, Liu GD, Tan XY, Weng XF, Wu WZ, Zhou J, Wei XB. Real-time monitoring of rare circulating hepatocellular carcinoma cells in an orthotopic model by in vivo flow cytometry assesses resection on metastasis. Cancer Res. 2012, 72(10):2683-91. (corresponding author; impact factor: 9.3)
- Wang L, Zhu X, Xie C, Ding N, Weng X, Lu W, Wei X, Li C. Imaging acidosis in tumors using a pH-activated near-infrared fluorescence probe. Chem Commun (Camb). 2012, 11;48(95):11677-9. (corresponding author; impact factor: 6.7)
- Yan H, Wang L, Wang J, Weng X, Lei H, Wang X, Jiang L, Zhu J, Lu W, Wei X, Li C. Two-order targeted brain tumor imaging by using an optical/paramagnetic nanoprobe across the blood brain barrier. ACS Nano. 2012, 24;6(1):410-20. (corresponding author; impact factor: 12.0)
- Hu L, Fan Z, Du H, Ni R, Zhang S, Yin K, Ye J, Zhang Y, Wei X, Zhang X, Gross PL, Kunapuli SP, Ding Z. BF061, a novel antiplatelet and antithrombotic agent targeting P2Y₁₂ receptor and phosphodiesterase. Thromb Haemost. 2011, 106(6):1203-14. (impact factor: 5.8)
- Li C, Li K, Yan H, Li G, Xia J, Wei X. Dextran based pH-activated near-infrared fluorescence nanoprobe imaging the acidic compartments in cancer cells. Chem Commun (Camb). 2010, 46(8):1326-8. (corresponding author; impact factor: 6.7)
- Sipkins DA, Wei X, Wu JW, Runnels JM, Cote D, Means TK, Luster AD, Scadden DT, Lin CP. In vivo imaging of specialized bone marrow endothelial microdomains for tumor engraftment. Nature. 2005, 435:969-73. (impact factor: 42.4).
- Georgakoudi I, Solban N, Novak J, Rice, W, Wei X, Hasan, T, Lin CP. In vivo flow cytometry: A new method for enumerating circulating cancer cells. Cancer Research. 2004, 64:5044-7 (impact factor: 9.3).
- Kunstfeld R, Hirakawa S, Hong YK, Lin, CP, Wei X, Bohlen P, Detmar. Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia. Blood. 2004, 104:1048-57 (impact factor: 9.8).
- Wei X, Tromberg BJ, Cahalan MD. Mapping the sensitivity of T cells with an optical trap: polarity and minimal number of receptors for Ca(2+) signaling. Proc Natl Acad Sci U S A. 1999, 96(15):8471-6.(impact factor: 9.8).