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Viper Medical Scientist Profile: Shangguan Guangying

2025-11-03

PhD in Electronic Engineering and Physics, University of Dundee, UK

Research Directions

  • Biomedical Photonics
  • Technical Development of Optical Coherence Imaging and Its Functional Imaging
  • Medical Instrument Development
  • System Control
  • Material Analysis

Research Experience

  • 2014-2016: Department of Engineering, Faculty of Engineering and Manufacturing Technology, University of Nottingham, UK; Department of Electronic and Electrical Engineering, University of Sheffield, UKCollaborated with Professor Adam Clare and his team at the University of Nottingham on additive manufacturing research. Also worked with the optics laboratory led by Dr. Kristian Groom at the University of Sheffield on the following projects:

Research Experience

2010-2014

Department of Engineering, Mathematics and Physics, University of Dundee, UK; Department of Bioengineering, University of Washington, USA

  • Development of dual-camera OCT (Optical Coherence Tomography) angiography.
  • Application of photothermal OCT in imaging the distribution of gold nanoparticles in mouse lymph nodes.
  • Prediction of drug concentration and imaging via OCT.
  • Measurement of the microstructure and vibration of guinea pig cochlear implants in vitro and in vivo using phase-sensitive OCT.
  • Development of quantitative OCT algorithms.
  • Quantitative determination of the biomechanical properties of skin by combining surface acoustic wave (SAW) method with phase-sensitive OCT (PhS-OCT).
  • Measurement of the mechanical properties of scaffolds for tissue engineering.

2009

Department of Engineering, Mathematics and Physics, University of Dundee, UK

  • Research and development of TMM (Tissue Mimicking Material) ultrasonic imaging.

2006-2007

School of Precision Instrument and Opto-Electronics Engineering, Tianjin University, China

  • Design of THz (Terahertz) detection sensors for clinical applications.
  • Research on imaging flow cytometers.
  • Development of amplifiers for ECG (Electrocardiogram) and EEG (Electroencephalogram).

PUBLICATIONS

Peer reviewed journal paper

  1. Ling Yuting, Chunhui Li, Kanheng Zhou, Guangying Guan, Paul L Appleton, stephen Lang, David McGloin, Zhihong Huang & Ghulam Nabi, Microscale characterization of prostate biopsies tissues using optical coherence elastography and second harmonic generation imaging, Laboratory Investigation volume 98, pages 380-390 (2017)
  2. Hirsch, Matthias & Patel, Rikesh & Li, Wenqi & Guan, Guangying & Leach Richard & D. Sharples, steve & Clare, Adam. (2016) Assessing the capability of in-situ nondestructive analysis during layer based additive manufacture. Additive Manufacturing. 13. 135-142
  3. Guan G, Hirsch M, Syam W P, et al. Loose powder detection and surface characterization in selective laser sintering via optical coherence tomography[C]//Proc. R. Soc. A. The Royal Society, 2016, 472(2191): 20160201. (IF: 2.05)
  4. Guangying Guan, Matthias Hirsch, Zeng Hai Lu, David T D Childs, Stephen J Matcher, Ruth Goodridge, Kristian M Groom, Adam T Clare, ‘Evaluation of Selective Laser Sintering Processes by Optical Coherence Tomography’, Materials & Design. 2015;88:837-46. (IF: 3.997)
  5. Chunhui Li, Guangying Guan, Yuting Ling, Ying-Ting Hsu, Shaozhen Song, Jeffrey T.-J. Huang, Stephen Lang, Ruikang K. Wang, Zhihong Huang and Ghulam Nabi, ‘Detection and characterisation of biopsy tissue using quantitative optical coherence elastogaphy (OCE) in men with suspected prostate cancer’, Cancer Letters, 2015, 357(1): 121-128. (IF: 5.016)
  6. Chunhui Li, Guangying Guan, Fan Zhang, Ruikang K. Wang, Zhihong Huang, and Ghulam Nabi, ‘Quantitative elasticity measurement of urinary bladder wall using laser-induced surface acoustic waves’, Biomedical Optics Express, 2014, 5(12): 4313–4328. (IF: 3.497)
  7. Chunhui Li, Guangying Guan, Fan Zhang, Ghulam Nabi, Ruikang K. Wang and Zhihong Hhuang, ‘Laser induced surface acoustic wave combined with phase sensitive optical coherence tomography for superficial tissue characterization: a solution for practical application’, Biomedical Optics Express, 2014, 5(5): 1403-1418. (IF: 3.497)
  8. Guan, G, Li, C, Ling, Y, Yang, Y, Vorstius, JB, Keatch, RP, Wang, RK & Huang, Z, 'Quantitative evaluation of degenerated tendon model using combined optical coherence elastography and acoustic radiation force method' Journal of Biomedical Optics, vol. 18, no. 11, 111417 (2013). (IF: 2.752)
  9. Chunhui Li, Shaozhen Song, Guangying Guan, Ruikang K Wang, Zhihong Huang, “Frequency dependence of laser ultrasonic SAW phase velocities measurements.”, Ultrasonics. 06/2012; DOI:10.1016/j.ultras.2012.05.009 (IF: 1.649)
  10. Chunhui Li, Guangying Guan, Sinan Li, Zhihong Huang, Ruikang K Wang, “Evaluating elastic properties of heterogeneous soft tissue by surface acoustic waves detected by phase-sensitive optical coherence tomography.” Journal of Biomedical Optics. 05/2012; 17(5):057002. (IF: 2.752)
  11. Chunhui Li, G Guan, Z Huang, M Johnstone, R K Wang, “Noncontact all-optical measurement of corneal elasticity.” Optics Letters. 05/2012; 37(10):1625-7. (IF: 3.179)
  12. Chunhui Li, Guangying Guan, Xi Cheng, Zhihong Huang, Ruikang K Wang, “Quantitative elastography provided by surface acoustic waves measured by phase-sensitive optical coherence tomography.” Optics Letters. 02/2012; 37(4):722-4. (IF: 3.179)
  13. Yeongri Jung, Guangying Guan, Chen-Wei Wei, Roberto Reif, Xiaohu Gao, Matthew O'Donnell, Ruikang K Wang, “Multifunctional nanoprobe to enhance the utility of optical based imaging techniques.” Journal of Biomedical Optics. 01/2012; 17(1):016015. (IF: 2.752)
  14. Chunhui Li, Sinan Li, Guangying Guan, Cheng Wei, Zhihong Huang, Ruikang K Wang, “A comparison of laser ultrasound measurements and finite element simulations for evaluating the elastic properties of tissue mimicking phantoms”, Optics & Laser Technology. 01/2012; 44:866 - 871. (IF: 1.649)
  15. Guangying Guan, Roberto Reif, Zhihong Huang, Ruikang K Wang, “Depth profiling of photothermal compound concentrations using phase sensitive optical coherence tomography.”Journal of Biomedical Optics. 12/2011; 16(12):126003. (IF: 2.752)
  16. Chunhui Li, Guangying Guan, Roberto Reif, Zhihong Huang, Ruikang K Wang, “Determining elastic properties of skin by measuring surface waves from an impulse mechanical stimulus using phase-sensitive optical coherence tomography.” Journal of The Royal Society Interface. 11/2011; 9(70):831-41. (IF: 4.907)
  17. Lin An, Guangying Guan, Ruikang K Wang, “High-speed 1310 nm-band spectral domain optical coherence tomography at 184,000 lines per second”, Journal of Biomedical Optics. 06/2011; 16(6):060506. (IF: 2.752)
  18. Guangying Guan, Chunhui Li, Hui Shi, “Optical coherence tomography (OCT) in Brain and neural imaging”, International Journal of Biomedical Engineering, 2008, vol. 31, issue. 6, pp. 342-347.

Peer reviewed conference paper

  1. Guan G, Song S, Huang Z, et al. Application of new optical coherence elastography to monitor the mineralization processing in bone tissue engineering constructs[C]//SPIE BiOS. International Society for Optics and Photonics, 2015: 93220G-93220G-8.
  2. Guangying Guan; Roberto Reif; Ruikang K. Wang, “Depth profile absorber concentration reconstruction using photothermal optical coherence tomography” Proc. SPIE 8213, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI, 82132G (February 9, 2012);